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Monthly Archives : March, 2010

The Many Faces of Autism: From Behavior to Biology

The Autism News | English

By University of California Television

Dr. Robin Hansen, Director of Clinical Program at the UC Davis MIND Institute explores the current research on the heterogeneity of autism spectrum disorders in terms of both behavior and biology, and advances in knowledge of etiology and application for treatments. Series: M.I.N.D. Institute Lecture Series on Neurodevelopmental Disorders [4/2010] [Health and Medicine] [Professional Medical Education] [Show ID: 17653]

Source: YouTube

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The Autism News English, English autism, autistic, behavior, Biology, heterogeneity, Robin Hansen, treatment (more…)

Newer Genetic Test for Autism More Effective

The Autism News | English

Study finds chromosomal microarray analysis detects more abnormalities

By Jenifer Goodwin | HealthDay Reporter

A newer type of genetic test is better at detecting abnormalities that predispose a child to autism than standard genetic tests, new research has determined.

Researchers offered about 933 people aged 13 months to 22 years who had been diagnosed with an autism spectrum disorder three genetic tests: G-banded karyotype testing, fragile X testing or chromosomal microarray analysis (CMA), which has been available only for the past few years.

Karyotype tests identified chromosomal aberrations associated with autism in about 2 percent of patients, while the fragile X genetic mutation was found in about 0.5 percent of patients.

CMA detected chromosomal abnormalities in slightly more than 7 percent of patients, making it the best available genetic test for autism spectrum disorders, the study authors said.

“The CMA test alone has triple the detection rate of karyotyping or fragile X,” said co-senior author Bai-Lin Wu, director of the Genetics Diagnostic Laboratory at Children’s Hospital Boston. “CMA should be added to first-tier genetic testing for autism spectrum disorders.”

The study appeared online March 15 and will be published in the April print issue of Pediatrics.

“When parents have a child diagnosed with an autism spectrum disorder, one of the first questions they often ask is ‘how did this happen?’ ” said Dr. Robert Marion, a pediatric geneticist at Children’s Hospital at Montefiore Medical Center in New York City.

“In the vast majority of cases, we believe there is at least a genetic predisposition to autism, but the ability to identify a specific genetic cause has been very elusive,” Marion said. “Part of that is because of the technology that’s been available. A larger part is at this point, we just don’t fully understand what the genetic mechanism that leads to autism is.”

Standard practice is to offer children with autism two tests as a first-line genetic work-up: karyotype and fragile X testing, the researchers said.

In karyotyping, forms of which have been around since the 1960s, geneticists use a microscope to look for chromosomal abnormalities that are associated with autism, explained Dr. David Miller, a clinical geneticist and assistant director of the Genetics Diagnostic Laboratory at Children’s Hospital Boston, which conducted the new research along with Boston’s Autism Consortium.

Like karyotyping, CMA also looks for chromosomal abnormalities, but does so at 100 times the resolution of the earlier test, Miller said. CMA, a genome-wide test, can identify sub-microscopic deletions of duplications of DNA sequences, called copy-number variants, known to be associated with autism, he said. (more…)

Teacher faces sack for writing ‘loser’ on poor exam paper

The Autism News | English

By Associated Press | Fox 8

The mother of a sixth grade student in Buncombe County, North Carolina says her daughter’s teacher wrote ‘loser’ on the girl’s class assignments and she’s speaking out about the discouraging comments.

Source: http://www.fox8.com/videobeta/bb6ff0c4-bdbb-47f6-aa8f-ea9557855996/News/Teacher-writes-Loser-on-child-s-assignments

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The Autism News English, English Buncombe County, losers, North Carolina, sixth grade student, teacher

Eric’s world

The Autism News | English


Eric Fritz yells with joy as he plays in shaving cream at Wyoming Valley Children’s Association. (Photo by FRED ADAMS/FOR THE TIMeS LEADER)

By Mary Therese Biebel | Times Leader

He squirms. He twists. He bounces up and down.

Anyone can see it’s not easy for 4-year-old Eric Fritz to sit quietly at the little table in his preschool.

“C’mon, Eric. Stop,” a therapeutic support staff worker says, gently massaging the little boy’s shoulders and trying to hold his torso still.

It’s snack time at the Wyoming Valley Children’s Association in Forty Fort – and it’s time for Eric to pay attention to speech pathologist Terry Tokach, who has put Goldfish crackers, pumpernickel pretzels and pieces of shortbread cookie on the table.

“What do you want, Eric?” Tokach repeats again and again, holding out her hand. “Which one do you want?”

She doesn’t expect Eric to say “cracker” or “pretzel” – the little boy, who was diagnosed with autism when he was going on 2 years old – doesn’t communicate verbally.

But, Tokach hopes he will communicate another way, by picking up a picture of a “cracker” or “pretzel” and handing it to her.

Again and again, he simply grabs at the pretzels and crackers (not the cookies, which he doesn’t seem to like.) Again and again, Tokach steers his hand toward the appropriate picture.

When he finally hands her one, she rewards him with food and praise.

“Good job, Eric,” she tells the child, “I like it when you ‘talk’ to me. I like it when you look at me, too.”

A reluctance to engage in eye contact is one symptom of autism, a developmental disorder that, according to the national Centers for Disease Control and Prevention, affects 1 in 110 children to some extent.

Delayed verbal skills and tendencies toward hyperactivity and repetitive motions are other symptoms.

But, it was a lack of eye contact that first prompted Eric’s father, also named Eric, to suspect something was amiss.

“My husband noticed he wasn’t getting enough eye interaction,” Lori Fritz explained during an interview in the family’s Nanticoke home.

Young Eric also “had a few words, but they went away,” his mother said. “His speech isn’t there, so we do signing.”

Eric knows how to ask his parents for things he wants through sign language. The gesture for “milk” looks like you’re moving your hands to milk a cow. The gesture for “book” looks as if you’re opening the covers of a book.

“Eric’s come so far,” Lori Fritz, 37, said with a smile as Eric, her firstborn, climbed over his father’s lap and onto his shoulders, and leaned over to do a jigsaw puzzle on the floor.

“He’s good at puzzles,” said the elder Eric, who is 38.

The couple’s younger son, David, 2, favors dinosaurs, and played with several colorful ones on a recent evening.

“David likes to do everything Eric does, and Eric is usually pretty tolerant of David,” said the boys’ father, who gave up a job in sales and service to become “Mr. Mom.”

Eric’s job required out-of-state travel to cover a large territory, which caused him to miss out on a considerable amount of family time. With young Eric’s special needs, it made sense for Dad to give up his career.

“We definitely play it as a team,” said Lori, who kept her job in pharmaceutical sales. “What I’m good at doing, I do. What he’s good at doing, he does. For example, you would not want me to cook.”

Laughing, Eric the cook lets on that he likes to make homemade chili and spaghetti sauce.

A typical day for young Eric involves getting up around 7 a.m., getting dressed, perhaps watching a cartoon, and seeing a TSS worker from 8:30 to 11:30 a.m.

From noon to 2:30 most days, he attends a preschool program at the children’s association, where he is in a class of seven students, each of whom receives lots of one-on-one attention.

On Mondays and Wednesdays a TSS worker spends time with him at home in the late afternoon, and every day there are familiar routines of supper, bath, story time and songs. Bedtime is about 9:30 p.m.

“He’s less resistant to going to bed than he used to be,” his father said.

Rejoicing in small triumphs

Children with autism tend to become overwhelmed by certain stimuli – it could be too many bright colors, too many people, or a whiff of a stranger’s perfume, Lori Fritz explained.

“Eric isn’t a fan of crowds,” she said.

To cope, children with autism sometimes “self-stimulate,” using repetitive motions or sounds to distract themselves from the overwhelming stimuli.

In addition to sights, sounds and aromas, textures can be a challenge.

Eric, for example, doesn’t like the way rice feels, his mother said.

Yet he doesn’t have a problem with shaving cream.

That became apparent on a recent afternoon when the staff at Eric’s preschool had an exercise designed to help the class become accustomed to the smoothness of the cream.

Teacher’s aide Cathy Wolfe spread some foam on a table and Eric plunged his hands into it with gusto.

Later that day, after his session with the speech pathologist, he met with occupational therapist Shari Aude, who soon had him coloring a picture of a bear with crayons, then finger-painting various shapes and lines.

“This is to get him used to the idea of holding a pencil,” Aude said.

One part of his therapy Eric really seemed to enjoy was swinging on his stomach in a contraption called a “prone swing” or “vestibular swing.”

Lying in a canvas swing that was suspended from the ceiling and hanging just a few inches above a thick rubber mat on the floor, Eric reached down to the mat with his hands and propelled himself around.

“This is to help him understand his place in space, to deal with gravitational insecurity,” Aude said. “It’s exercising his arms and hands too, and that will be helpful for holding a pencil. That’s something he needs for kindergarten readiness.”

What kind of school Eric eventually attends is a matter as yet undecided, his dad said, and it’s hard to predict what his life will be like as an adult. Web sites devoted to autism suggest careers as diverse as caring for animals or searching for abnormal cells on a microscope slide can be ideal for some with autism.

For now, Eric’s parents rejoice in the small triumphs, as when their son communicates through sign language or obeys a simple request, perhaps to put away a toy.

He does seem to be in perpetual motion, and the reason for all that jumping and running around sometimes mystifies his parents.

“We don’t know if he’s being willful,” Lori Fritz said. “Or is it because he can’t help it?”


The Fritz family of Nanticoke relaxes in the family room of their Nanticoke home. Lori, left, watches her husband, Eric, and son Eric, 4, play. (photo by Pete G. Wilcox/The Times Leader)

Source: http://www.timesleader.com/features/Eric_rsquo_s_world_03-14-2010.html

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The Autism News English autism, autistic, Eric’s world, Fritz family, Nanticoke

Autism disorder treatment, without medication

The Autism News | English

By Danica Lawrence | KIKD CBS 3

IDAHO FALLS – Each of the Perfili’s children struggle with, fighting, academics, and most of all, a short attention span. They suffer from different autism disorders.

Over the last 6 weeks they have been seeing Dr. Brady Wirick. He has found a way to help with just exercise.

“We have seen the most improvements with Ashton, he’s the one we started with,” says mother Linda Perfili. “His behavior was very unpredictable, and he was very aggressive and so he would hurt his friends not even trying to, and this week alone he’s played with his friends every single day so we are seeing huge improvements with him.”

Dr.Wirick explains how these exercises are stimulating the right side of the children’s brain. It’s the right side that is underdeveloped.

“So their left brain is firing at a rate up here and the right brain is firing at a rate down here, so what the treatment you saw is doing is those are all right brain specific exercises and so what that is going to do is level out and balances their brain to the point where they can function at a quote on quote normal activity level,” says Dr. Wirick.

The Perfili’s have tried medication before but haven’t seen the results Dr.Wirick has given them.

“It seems like we’ve tried everything,” says Linda Perfili.

“So if you have a kid whose right brain’s here and left brain is here, and you medicate them, you’ll bring them down, but it’s going to bring both of them down,” says chiropractic neurologist Dr. Brady Wirick.

And bringing both sides down won’t solve the problem. You have to strengthen the right side. Every morning Ashton, Mackenzie, and Nephi practice each exercise for couple minutes. They tap their hands on their sides, march in place, and move their arms in a circle and clap.

“When they are clapping in big circles, it’s forcing them to keep a beat, which is a right brain activity as well as moving big joints,” says Dr. Wirick.

Each child is improving but Ashton is taking strides.

“I think what it does is it makes a connection, and puts him more in balance because he can’t balance himself,” says father, Justin Perfili.

Dr. Wirick believes it will be another six to nine months before the Perfili’s kids’ right brains are stronger.

Source: http://www.kidk.com/news/local/87628697.html

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The Autism News English, English, English autism, autism disorders, autistic, Dr. Brady, Dr. Wirick, right brain